ADHD & PMDD – Is there a connection?


Research shows that the prevalence of PMDD is significantly higher in women with ADHD, compared to women without (approx. 10 fold!).

Most women who have ADHD & PMDD, know that PMDD symptoms can make ADHD symptoms worse; these include symptoms associated with focus and concentration which often aggravate in the lead up to menstruation.


Well, this happens in part due to the fact that hormones such as oestrogen regulate neurotransmitters such as dopamine. Sensitivity to fluctuations in hormones like oestrogen, which drops after ovulation, and again mid-luteal, lead to interference with transmission of dopamine which subsequently aggravates ADHD symptoms.

To ensure ADHD symptoms are not worse in the luteal phase of the cycle, supporting hormonal balance and the resultant fluctuations in neurotransmitters such as dopamine is a key part to feeling better.

Ref: Dorani F, Bijlenga D, Beekman ATF, van Someren EJW, Kooij JJS. Prevalence of hormone-related mood disorder symptoms in women with ADHD. J Psychiatr Res. 2021 Jan;133:10-15. doi: 10.1016/j.jpsychires.2020.12.005. Epub 2020 Dec 3. PMID: 33302160.

Like this article?

Share on Facebook
Share on Twitter
Share on Linkdin
Share on Pinterest

Leave a comment

More Articles


PMMD: What is it?

Pre-menstrual Dysphoric Disorder (PMDD) is a severe type of premenstrual syndrome. It is characterised by moderate to severe affective and behavioural symptoms, that occur post

Read More »
Immune System

Five ways to reduce inflammation

Inflammation is a defence mechanism initiated by the immune system in response to perceived threat such as a virus, dietary antigen or auto-immune disease[i]. The

Read More »

Subscribe to the Newsletter